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First-Line Psychosocial Care for Children and Adolescents on Antipsychotics (APP)

What does the APP measure assess?

  • The APP measure assesses the percentage of children and adolescents 1 to 17 years of age who had a new prescription for an antipsychotic medication, without a clinical indication and had documentation of psychosocial care as first-line treatment (90 days prior to new prescription through 30 days after).1

Why is the APP measure important?

  • Prescribing antipsychotic medications to children and adolescents for which psychosocial interventions are considered first-line treatment has increased. Antipsychotic medications can elevate the risk for developing serious metabolic health conditions like heart disease, diabetes, stroke and other health problems into adulthood.2
  • Psychosocial care, which includes behavioral interventions, psychological therapies, and skills training among other forms of non-pharmacological care, is the recommended first-line treatment option for children and adolescents diagnosed with nonpsychotic conditions such as attention-deficit disorder and disruptive behaviors.

What can you do to help?

  • Before prescribing children and adolescents any antipsychotic medication, you should complete or refer your patients for a trial of first-line, evidenced-based psychosocial care.
  • When prescribed, antipsychotic medications should be part of a comprehensive, multi-modal plan for coordinated treatment that includes psychosocial care.
  • Periodically the ongoing need for continued therapy with antipsychotic medications should be reviewed.

Antipsychotic Medications

DescriptionPrescription
Miscellaneous antipsychotic agents
  • Aripiprazole
  • Asenapine
  • Brexpiprazole
  • Cariprazine
  • Clozapine
  • Haloperidol
  • Iloperidone
  • Loxapine
  • Lurisadone
  • Molindone
  • Olanzapine
  • Paliperidone
  • Pimozide
  • Quetiapine
  • Risperidone
  • Ziprasidone
Phenothiazine antipsychotics
  • Chlorpromazine 
  • Fluphenazine 
  • Perphenazine 
  • Thioridazine 
  • Trifluoperazine
Thioxanthenes
  • Thiothixene
Long-acting injections
  • Aripiprazole 
  • Fluphenazine decanoate 
  • Haloperidol decanoate 
  • Olanzapine 
  • Paliperidone palmitate 
  • Risperidone


Antipsychotic Combination Medications

DescriptionPrescription
Psychotherapeutic combinations
  • Fluoxetine-olanzapine
  • Perphenazine-amitriptyline

HEDIS® is a registered trademark of the National Committee for Quality Assurance (NCQA).

CPT® Codes for Psychological Care:

90832 - 90834, 90836 - 90840, 90845 - 90847, 90849, 90853, 90875, 90876, 90880

HCPCS Codes for Psychological Care:

G0176, G0177, G0409 - G0411, H0004, H0035 - H0040, H2000, H2001, H2011 - H2014, H2017 - H2020, S0201, S9480, S9484, S9485 With or without a telehealth modifier: 95, GT